The cardiovascular diseases are the first cause of morby mortality in the West and the second cause of death in Colombia. It has been considered that in Colombia are five coronary events per hour and 45 deaths to the day by this one disease take place. In order to establish the prevalence of IAM and the personal factors of risk in relation to mortality by IAM in the University Hospital San Ignacio 1999-2005, a retrospective lingitudinal study was made, by means of the analysis of 2022 registries of hospitable debit of patients with IAM and the revision of 140 clinical histories of the debits with IAM diagnosis. The prevalence was of 61.59+- 13.86 years. 65% were men and 35% women. The reason man-woman was 1:0.4. 61% presented/displayed arterial hypertension, 58% dislipidemia, 53% other cardiopathies. 51 % tabaquismo and 25% familiar antecedents. To belong to masculine sex (OR 1.3), to have arterial hypertension (OR 3.3), diabetes mellitus tipo II (OR 2.34); obesity (OR 1.09); previous cardiopathy (OR 1.04) and to be sedentary (OR 2.05) increases the risk of dying by IAM. Masculine sex associated to the age outpost, arterial hypertension, dislipidemia and obesity constitute important factors of cardiovascular risk that they affect the increase of the prevalence of IAM and therefore to mortality by the same one. The IAM is maintaining a behavior maintained with tendency to the increase in the last seven years.