https://revistas.javeriana.edu.co/index.php/scientarium/issue/feed 2025-02-11T00:00:00-05:00 Juan Carlos Salcedo Reyes editorus@javeriana.edu.co Open Journal Systems <p><strong>Universitas Scientiarum:</strong> (ISSN: 0122-7483; E-ISSN: 2027-1352) is a multidisciplinary, Open-Acces, peer-reviewed, first-online journal devoted to the promotion of the recent progress in all fields of exact and natural sciences. The objective of Universitas Scientiarum is to publish timely (three times per year: April, August, and December), useful and informative results that will be of value to a general audience. All articles published in Universitas Scientiarum have undergone rigorous peer review by at least two international anonymous referees. Universitas Scientiarum was founded in 1987 by the Faculty of Sciences of the Pontificia Universidad Javeriana, Bogotá D.C., Colombia.</p> https://revistas.javeriana.edu.co/index.php/scientarium/article/view/37589 2023-07-01T13:27:36-05:00 Melissa Arango-Gil melissarg500@gmail.com Marcela Mora-López marce0384@hotmail.com Elizabeth Correa-Gómez elizabeth.correag@udea.edu.co Victor Manuel Osorio-Echeverri vmanuelo@gmail.com

<p>Most fungal infections are caused by species of the Candida genus, particularly C. albicans. The increasing number of strains developing resistance to antifungals, resulting in treatment failures, underscores the urgency of finding new antifungal agents. Since many bacteria of the genus Streptomyces produce molecules that inhibit fungal growth, this work aimed to evaluate the antifungal activity of three native isolates obtained from a rhizosphere and an artisanal composting system. Based on 16S RNA gene sequences, as well as biochemical and morphological traits, we identified S. globisporus, S. bacillaris, and S. cavourensis as the species most closely related to the S1H, S40, and S41 isolates, respectively. These species have been reported to produce antifungal compounds. The inhibition of Candida by antagonistic activity increased with longer Streptomyces incubation times, with no differences observed between Candida species. Few studies have simultaneously evaluated the inhibitory activity of Streptomyces isolates against different Candida strains. In this study, the isolates inhibited the growth of C. albicans, C. krusei, C. guilliermondii, C. glabrata, and C. lusitaniae, including strains resistant to fluconazole.</p>

2025-02-10T00:00:00-05:00 Copyright (c) 2025 Melissa Arango-Gil , Marcela Mora-López , Elizabeth Correa-Gómez , Victor Manuel Osorio-Echeverri