https://revistas.javeriana.edu.co/index.php/scientarium <p><strong>Universitas Scientiarum:</strong> (ISSN: 0122-7483; E-ISSN: 2027-1352) is a multidisciplinary, Open-Acces, peer-reviewed, first-online journal devoted to the promotion of the recent progress in all fields of exact and natural sciences. The objective of Universitas Scientiarum is to publish timely (three times per year: April, August, and December), useful and informative results that will be of value to a general audience. All articles published in Universitas Scientiarum have undergone rigorous peer review by at least two international anonymous referees. Universitas Scientiarum was founded in 1987 by the Faculty of Sciences of the Pontificia Universidad Javeriana, Bogotá D.C., Colombia.</p> Pontificia Universidad Javeriana en-US Universitas Scientiarum 0122-7483 <p><span id="aui_3_4_0_1_969" class="textos"><span id="aui_3_4_0_1_1007" style="line-height: 1.4;"><strong>Univ. Sci.</strong> is registered under a Creative Commons Attribution 4.0 International Public License. Thus, this work may be reproduced, distributed, and publicly shared in digital format, as long as the names of the authors and Pontificia Universidad Javeriana are acknowledged. Others are allowed to quote, adapt, transform, auto-archive, republish, and create based on this material, for any purpose (even commercial ones), provided the authorship is duly acknowledged, a link to the original work is provided, and it is specified if changes have been made. Pontificia Universidad Javeriana does not hold the rights of published works and the authors are solely responsible for the contents of their works; they keep the moral, intellectual, privacy, and publicity rights. Approving the intervention of the work (review, copy-editing, translation, layout) and the following outreach, are granted through an use license and not through an assignment of rights. This means the journal and Pontificia Universidad Javeriana cannot be held responsible for any ethical malpractice by the authors. As a consequence of the protection granted by the use license, the journal is not required to publish recantations or modify information already published, unless the errata stems from the editorial management process. Publishing contents in this journal does not generate royalties for contributors.</span></span></p> https://revistas.javeriana.edu.co/index.php/scientarium/article/view/37589 <p>Most fungal infections are caused by species of the Candida genus, particularly C. albicans. The increasing number of strains developing resistance to antifungals, resulting in treatment failures, underscores the urgency of finding new antifungal agents. Since many bacteria of the genus Streptomyces produce molecules that inhibit fungal growth, this work aimed to evaluate the antifungal activity of three native isolates obtained from a rhizosphere and an artisanal composting system. Based on 16S RNA gene sequences, as well as biochemical and morphological traits, we identified S. globisporus, S. bacillaris, and S. cavourensis as the species most closely related to the S1H, S40, and S41 isolates, respectively. These species have been reported to produce antifungal compounds. The inhibition of Candida by antagonistic activity increased with longer Streptomyces incubation times, with no differences observed between Candida species. Few studies have simultaneously evaluated the inhibitory activity of Streptomyces isolates against different Candida strains. In this study, the isolates inhibited the growth of C. albicans, C. krusei, C. guilliermondii, C. glabrata, and C. lusitaniae, including strains resistant to fluconazole.</p> Melissa Arango-Gil Marcela Mora-López Elizabeth Correa-Gómez Victor Manuel Osorio-Echeverri Copyright (c) 2025 Melissa Arango-Gil , Marcela Mora-López , Elizabeth Correa-Gómez , Victor Manuel Osorio-Echeverri https://creativecommons.org/licenses/by/4.0 2025-02-10 2025-02-10 1 20 10.11144/Javeriana.SC30.cotn