This essay takes up the tendencies that, within international relations, promote supra-national handling of certain zones of the planet. For the strategic value for humanity, these zones require special protection and collective responsibility given the virtual incapacity of the countries (which have sovereignty over the zones) to conserve them adequately. These tendencies are seen in the Amazon basin, which possesses characteristics that make the region desirable, not only as an eco-system, but aslo for the interests that are woven in its interior by state and private agents. To study these tendencies and interests, this study begins during the period of the cold war within the framework of the theoretical interpretations, which dominated at that moment. Then, the study moves up through the present time period when the presence of a series of conflictive factors in the Colombian Amazon, and a mistaken foreign policy, could justify the eventual application of these tendencies, which could bring grave consequence for Colombia, similar to the loss of Panama at the beginning of the twentieth century.