Publicado jun 30, 2013

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Walter A. Bretz

John G. Thomas

Robert J. Weyant



Objective: Develop a familial liability index for oral microbial status that reflects an imbalance of oral domains based on the presence of risk indicators in saliva, inter-proximal plaque, tongue, and throat. Methods: Fifty-six mother-child pairs from Webster and Nicholas counties, West Virginia, USA, participated in this study. Saliva samples were assayed for mutans streptococci (MS), interproximal plaque samples for the BANA Test (BT) species, tongue swabs for BT, and throat swabs for any of the sentinel organisms (Staphylococcus aureus, Streptococcus pyogenes, and yeasts). The corresponding thresholds for a (+) risk indicator were, respectively, ³105 CFU of MS salivary levels, one or more BT-(+) plaques (>105 CFU/mg of plaque of at least one of BT-(+) species), weak-(+) BT for a tongue swab (>104-<105), and >104 CFU/swab for any of the sentinel markers. Results: The mean age of mothers and children was 41.6 and 14.6 years. Ninety-one % of both mothers and children had at least one (+) risk indicator. Overall, 76% of mother child-pairs had at least one (+) concordant oral microbial risk indicator. Accordingly, the relative risk (RR) of children having concordant results with their mothers was increased 1.36 (BT-plaque), 1.37 (BT-tongue), 0.94 (sentinel organisms) and 1.13 (MS) times. Principal component analysis revealed distinct sets of oral microbial risk indicators in mothers and children that correlated with dental caries prevalence rates in children. Conclusions: Mother-child pairs shared similarities of oral microbial risk indicators that allow for the development of a liability index that can elucidate caries in the children.


Objetivo: Desarrollar un índice de responsabilidad familiar para el estado microbiano oral que refleja un imbalance de los dominios orales con base en la presencia de indicadores de riesgo en saliva, placa interproximal, lengua y garganta. Métodos: 56 parejas madre-hijo de los condados Webster y Nicholas, West Virgina, Estados Unidos, participaron en el estudio. Se analizaron muestras de saliva para Streptococcus mutans (Sm), placa interproximal y lengua (prueba de BANA), torundas de algodón para BANA, y garganta para organismos centinelas (Staphylococcus aureus, Streptococcus pyogenes y levaduras). Los umbrales correspondientes para un indicador de riesgo positivo fueron respectivamente ³ 105 UFC de niveles salivales de Sm, > 1 placas BANA positivas (> 105 UFC/mg de al menos una especie BANA positiva), BANA débil para torundas de lengua (> 104-< 105), y > 104 UFC/torunda de cualquier marcador centinela. Resultados: Las edades promedio de madres e hijos fueron 41,6 y 14,6 años. El 91 % madres y niños tenían al menos un indicador de riesgo positivo. El 76 % de las parejas madre-hijo tenían al menos un indicador concordante de riesgo microbiano oral. Así mismo, el riesgo relativo de los niños con resultados concordantes con sus madres aumentó 1,36 (BANA-placa) 1,37 (BANA-lengua), 0,94 (organismos centinela) y 1,13 (Sm) veces. El análisis de componente principal reveló distintos grupos de indicadores de riesgo microbiano oral en madres e hijos que se correlacionaron con la prevalencia de caries en los hijos. Conclusiones: Las parejas madre-hijo compartieron indicadores de riesgo microbiano oral similares que permiten desarrollar un índice de responsabilidad que pueda dilucidar caries en los hijos.

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Cómo citar
Bretz, W. A., Thomas, J. G., & Weyant, R. J. (2013). Familial Oral Microbial Imbalance and Dental Caries Occurrence in Their Children / Desequilibrio microbiano oral familiar y caries dental en los hijos. Universitas Odontologica, 32(68), 109–116. Recuperado a partir de
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