Keywords
Detoxification
Flocculation
Tetanus
Toxin.
How to Cite
Abstract
In order to reduce the incubation time and temperature in the Tetanic Toxin detoxification process, different times and temperature were evaluated; taking crops in process that were grown in tetanus Lab production of the National Institute of Health. To determine the exact da y of detoxification a logis tic model was established. The toxin was incubate at 4,22 and 37°C to estimate the optim temperature. Then the physical-chemical characteristics like (pH), and the biologycal characteristics (Lf/mL, unspecific, specific toxicity and antigenicy) of the toxoid were verified. The best conditions for the process are: 25 days of incubation at 37°C. With the characteristics above, yearly there is a possibility to get a profit of 1.513.350 doses that represen! $37.833.750 for the production of the Tetanic Toxin
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