Keywords
neoplasie
platelets
refractory state.
How to Cite
Abstract
Development of permanent platelet refractoriness is a majar problem in multitransfused patients with hematologicmalignancies. Tbe systematic leukocyte reduction of blood components transfused, guided to reduce it, mayincrease the cost of the transfusional therapy, specially by the application of leukocyte adsorption filters. Westudied the development of platelet refractoriness in 83 patients with hematologic malignancies, that had beentransfunded with platelet concentrates derived from Buffy Coat, with or without the use of leukocyte depletionfilters. No significant difference (p = 0.378) was found between both groups; for the refractoriness development.Additionally, the cost of the therapy increased about four times, (p<O.OOO 1) when the filters applied.
Univ. Sci. is registered under a Creative Commons Attribution 4.0 International Public License. Thus, this work may be reproduced, distributed, and publicly shared in digital format, as long as the names of the authors and Pontificia Universidad Javeriana are acknowledged. Others are allowed to quote, adapt, transform, auto-archive, republish, and create based on this material, for any purpose (even commercial ones), provided the authorship is duly acknowledged, a link to the original work is provided, and it is specified if changes have been made. Pontificia Universidad Javeriana does not hold the rights of published works and the authors are solely responsible for the contents of their works; they keep the moral, intellectual, privacy, and publicity rights. Approving the intervention of the work (review, copy-editing, translation, layout) and the following outreach, are granted through an use license and not through an assignment of rights. This means the journal and Pontificia Universidad Javeriana cannot be held responsible for any ethical malpractice by the authors. As a consequence of the protection granted by the use license, the journal is not required to publish recantations or modify information already published, unless the errata stems from the editorial management process. Publishing contents in this journal does not generate royalties for contributors.