Tuberculosis in Patients with Solid Organ Transplantation
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Introduction: In patients undergoing solid organ transplantation, tuberculosis remains a common complication, especially in high endemic countries.
Aims: To determine the presentation of tuberculosis in patients undergoing solid organ transplantation, to describe their demographic characteristics and its evolution, and to conduct a literature review.
Material and Methods: This article was a descriptive retrospective study of case series of tuberculosis in patients undergoing heart or kidney transplantation, between June 2004 and April 2011, at the Hospital Universitario San Ignacio in Bogotá, Colombia. Demographic characteristics, evolution and outcome were determined.
Results: Tuberculosis was diagnosed in 3 patients undergoing solid organ transplantation out of 187 patients, 2 cases of pulmonary tuberculosis and one by hematogenous spread in patients with kidney and heart transplantation, respectively. One of them had co-infection with pulmonary histoplasmosis. One of the three patients died during anti-tuberculosis treatment.
Conclusions: Given the prevalence of the disease in our country, patients on the waiting list for transplantation should be evaluated for latent tuberculosis. Additionally, transplant patients are at increased risk of infections which should be taken into account in the differential diagnosis of respiratory infectious diseases.
Tuberculosis, organ, transplantation, tuberculosis, trasplante, órgano,
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