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Rafael Gustavo Castellanos Garzón

Elkin Rene Barrios Peralta

Alberto Adolfo Vides Velásquez

Maria Francisca Olarte

Resumen

La intoxicación por acetaminofén es una de las causas más frecuentes de falla hepática aguda fulminante y una de las principales causas de atención en los servicios de urgencias, por intoxicación debida a medicamentos. Recientemente, se han registrado avances en la comprensión fisiopatológica, diagnóstico y tratamiento de esta entidad clínica. Los mecanismos de estrés oxidativo y daño del ADN mitocondrial explican los daños producidos en esta intoxicación. En esta revisión se presentan aspectos referentes a la epidemiología, mecanismos fisiopatológicos, diagnóstico y tratamiento de la intoxicación por acetaminofén.

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Keywords

sobredosis de droga; acetaminofén; enfermedad hepática inducida por drogas y medicamentos.

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Cómo citar
Castellanos Garzón, R., Barrios Peralta, E., Vides Velásquez, A., & Olarte, M. (2018). Actualización en la comprensión y manejo de la intoxicación por acetaminofén. Universitas Medica, 59(4), 1-11. https://doi.org/10.11144/Javeriana.umed59-4.acet
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