Abstract
Introduction: General anesthesia divides in different stages where one of the most critical is the induction of anesthesia and the drugs used in it. Propofol and Ketamine being the most recognized
Objective: Conduct a review of the pharmacokinetic and pharmacodynamic properties of these two drugs, for making decisions about situations in which each of them should be used separately or concomitant
Materials and methods: Four separate searches in the PUBMED database where performed, obtaining a total of 27 bibliographies for the review
Results: Propofol is a hypnotic agent used for short procedures in patients that are hemodynamically stable. Ketamine has a pharmacodynamic properties that are ideal for patients with hemodynamic instability. Ketofol is a drug alternative that achieves synergism, allowing the benefits of each of these drugs to be maintained and reducing the probability of adverse effects
Conclusion: Depending on the procedure to be performed and the hemodynamic stability of each patient one drug may be preferred over another
Key words: Anesthesia, Anesthesia induction, Propofol, Ketamine, Ketofol

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Copyright (c) 2023 Jesús Andrés Henao Zapata, Catalina Herrera-Echeverry, Jorge Steven Montealegre Arturo, Rafael Ordoñez-Lizarralde, Juan Camilo Valbuena Pabón