Publicado ene 31, 2024



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Natalia Coriat-Cruz https://orcid.org/0000-0002-1631-4894

Freddy Moreno-Gómez https://orcid.org/0000-0003-0394-9417

Sofía Cepeda-Londoño https://orcid.org/0009-0001-7333-2706

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Resumen

Para esta revisión de la literatura, se describieron las propuestas planteadas para el manejo farmacológico de la infección por viruela del mono (Mpox) durante el brote de 2022. Con ese objetivo, se realizó una búsqueda sistematizada de la literatura utilizando las palabras claves: infections, monkeypox, therapeutics, treatment efficacy en Medline, a través de PubMed, donde se identificaron 54 artículos publicados desde 2001 a 2023, de los cuales se seleccionaron 26 para ser incluidos en los resultados. Se encontró que los tratamientos más documentados para tratar la infección por Mpox fueron el tecovirimat, seguido del cidofovir y del brincidofovir. El tecovirimat fue la opción terapéutica más segura y eficaz, con la capacidad en reducir la carga viral del Mpox con una tasa de supervivencia de al menos un 90 %. Sin embargo, ninguno de los tres medicamentos los ha aprobado la Administración de Alimentos y Medicamentos de los Estados Unidos para el tratamiento del Mpox, por lo que se reconoce la importancia de llevar a cabo estudios dirigidos para establecer esquemas de tratamiento mundial, considerando que el Mpox es una potencial arma biológica para todo el planeta.

Keywords

Infections, Monkeypox, Therapeutics, Treatment Efficacy, Orthopoxvirus

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Cómo citar
Coriat-Cruz, N., Moreno-Gómez, F., & Cepeda-Londoño, S. (2024). Espectro de manejo farmacológico de la infección por viruela del mono durante el brote de 2022. Universitas Medica, 64(4). https://doi.org/10.11144/Javeriana.umed64-4.vmon
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Artículos de revisión