Cocaine-Induced Severe Bronchospasm: A Case Report
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The consumption of psychoactive substances represents today in our country and worldwide a public health problem. Among these, cocaine occupies an important place, in terms of frequency of consumption, associated with the need to use emergency medical services due to complications derived from intoxication and overdose with exposure to it. The clinical effects are fully characterized, but within these the presence of bronchospasm is not clearly and commonly identified. Among the risk factors for its generation, we find inhalation exposure and patient comorbidity, among which asthma accounts for the vast majority of cases. For this reason, it is important to identify said complication associated with contact with this substance, which is why we present a case in which the patient develops severe bronchospasm with a requirement for mechanical ventilation.
2. Boghdadi MS, Henning RJ. Cocaine: Pathophysiology and clinical toxicology. Hear Lung J Acute Crit Care. 1997;26(6):466–83.
3. Departamento Administrativo Nacional de Estadistica. Boletín Técnico Encuesta Nacional De Consumo De Sustancias Boletín Técnico. 2020;1–34. Available from: https://www.dane.gov.co/files/investigaciones/boletines/encspa/bt-encspa-2019.pdf
4. Zimmerman JL. Cocaine Intoxication. Crit Care Clin [Internet]. 2012;28(4):517–26. Available from: http://dx.doi.org/10.1016/j.ccc.2012.07.003
5. Kim ST, Park T. Acute and chronic effects of cocaine on cardiovascular health. Int J Mol Sci. 2019;20(3):1–22.
6. Havakuk O, Rezkalla SH, Kloner RA. The Cardiovascular Effects of Cocaine. J Am Coll Cardiol. 2017;70(1):101–13.
7. Self TH, Shah SP, March KL, Sands CW. Asthma associated with the use of cocaine, heroin, and marijuana: A review of the evidence. J Asthma. 2017;54(7):714–22.
8. Osborn HH, Tang M, Bradley K, Duncan BR. New-onset bronchospasm or recrudescence of asthma associated with cocaine abuse. Acad Emerg Med. 1997;4(7):689–92.
9. Rome LA, Lippmann ML, Dalsey WC, Taggart P, Pomerantz S. Prevalence of cocaine use and its impact on asthma exacerbation in an urban population. Chest [Internet]. 2000;117(5):1324–9. Available from: http://dx.doi.org/10.1378/chest.117.5.1324
10. Levine M, Iliescu ME, Margellos-Anast H, Estarziau M, Ansell DA. The Effects of Cocaine and Heroin Use on Intubation Rates and Hospital Utilization in Patients With Acute Asthma Exacerbations. Chest [Internet]. 2005;128(4):1951–7. Available from: http://dx.doi.org/10.1016/S0012-3692(15)52588-9
11. Mohiuddin M, Zacharisen MC, Poulos C, Levy MB. Asthma deaths outside the hospital in an urban community from 2004 to 2008. Ann Allergy, Asthma Immunol [Internet]. 2012;108(6):412–7. Available from: http://dx.doi.org/10.1016/j.anai.2012.03.016
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