Publicado jul 4, 2023



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Felipe Botero-Rodríguez https://orcid.org/0000-0003-1537-5211

Ana María Zárate https://orcid.org/0000-0002-7591-5374

Damaris Cote Martínez https://orcid.org/0000-0001-5290-3699

Carlos Gómez Restrepo https://orcid.org/0000-0002-9013-5384

Andrés Duarte Osorio https://orcid.org/0000-0002-1982-6799

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Resumen

La esquizofrenia es un trastorno incapacitante del neurodesarrollo con una prevalencia a lo largo de la vida del 1 %. Algunos estudios han relacionado diversas enfermedades infecciosas con su incidencia y curso clínico, incluida la infección por Toxoplasma gondii. Este artículo es una revisión narrativa de la literatura, sobre la posible asociación entre la infección por T. gondii y la esquizofrenia. De 621 estudios, se utilizaron 34 que cumplieron con los criterios de selección. Se encontró una mayor incidencia de esquizofrenia en la descendencia de madres con antecedente de toxoplasmosis, a la vez que en adultos la infección se asoció con menor respuesta terapéutica, variación en días de hospitalización y mayor prevalencia. Sin embargo, las limitaciones metodológicas y los sesgos evidenciados en algunos de los estudios revisados sustentan la necesidad de conducir investigaciones que permitan determinar la validez de las asociaciones descritas.

Keywords

Toxoplasma, Toxoplasmosis, Congenital Toxoplasmosis, Public Health, SchizophreniaToxoplasma, Toxoplasmosis, Toxoplasmosis Congénita, Salud Pública, Esquizofrenia

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Cómo citar
Botero Rodríguez, F., Zárate, A. M., Cote Martínez, D., Gómez Restrepo, C., & Duarte Osorio, A. (2023). Infección por Toxoplasma gondii como factor de riesgo para desarrollar esquizofrenia: revisión de la literatura. Universitas Medica, 64(2). https://doi.org/10.11144/Javeriana.umed64-2.gond
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