Published Jul 4, 2023



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Natalia Andrea Lancheros Reina https://orcid.org/0000-0001-5180-1551

Nicole García https://orcid.org/0000-0002-6428-0676

Sonia María Restrepo Gualteros https://orcid.org/0000-0003-3870-4102

Andres Felipe Calderón https://orcid.org/0000-0001-6936-5284

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Abstract

In cystic fibrosis, respiratory infections represent the main cause of impaired lung function, mainly of bacterial etiology due to S. aureus, H. influenzae and P. aeruginosa, followed in frequency by infections by filamentous fungi such as Aspergillus fumigatus. Although it has been seen that the risk of developing allergic bronchopulmonary aspergillosis is higher in these patients, its diagnosis can sometimes be quite a challenge, so when pulmonary deterioration and frequent exacerbations occur, it is necessary to have a clinical suspicion and perform an immunological, clinical, and imaging approach, taking into account that its timely treatment reduces the risk of associated complications. A case of allergic bronchopulmonary aspergillosis in a pediatric patient with a history of cystic fibrosis is presented for its respective analysis taking into account its impact on clinical outcomes and disease progression.

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References
1. Maturu VN, Agarwal R. Prevalence of Aspergillus sensitization and allergic bronchopulmonary aspergillosis in cystic fibrosis: systematic review and meta-analysis. Clin Exp Allergy. 2015;45(12):1765-78. https://doi.org/10.1111/cea.12595
2. Lattanzi C, Messina G, Fainardi V, Tripodi MC, Pisi G, Esposito S. Allergic bronchopulmonary aspergillosis in children with cystic fibrosis: an update on the newest diagnostic tools and therapeutic approaches. Pathogens. 2020;9(9):716. https://doi.org/10.3390/pathogens9090716
3. Sunman B, Ademhan Tural D, Ozsezen B, Emiralioglu N, Yalcin E, Özçelik U. Current approach in the diagnosis and management of allergic bronchopulmonary aspergillosis in children with cystic fibrosis. Front Pediatr. 2020;8:582964. https://doi.org/10.3389/fped.2020.582964
4. Guzmán C, Parra G, Bozzo R, Pinochet MJ, Moreno M, Cofré F, et al. Prevalencia de aspergilosis broncopulmonar alérgica en niños con fibrosis quística. Neumol Pediátrica. 2021;16(2):81-4.
5. Belteton E, Chang A, Arriola MB. Aspergillosis broncopulmonar alérgica (aba) en fibrosis quística y su respuesta terapéutica. Guatem Pediátrica. 2016;20(2):28-31.
6. Maggiolo J, Rubilar L, González R, Girardi G, Vildósola C, Mendoza C. Aspergilosis broncopulmonar alérgica en niños con enfermedad pulmonar crónica y fibrosis quística. Rev Chil Pediátrica. 2006;77(2):161-8. https://doi.org/10.4067/S0370-41062006000200006
7. Jat KR, Walia DK, Khairwa A. Tratamiento anti‐IgE para la aspergilosis broncopulmonar alérgica en pacientes con fibrosis quística. Cochrane Database Syst Rev. 2021;3. https://doi.org/10.1002/14651858.CD010288.pub5
8. Rodríguez EC, López JMB, García IF, Fajardo IME, Cabanas AG. Conocimientos y tendencias actuales sobre la aspergilosis broncopulmonar alérgica. Rev Cuba Med Mil. 2021;50(2):20.
9. Manti S, Parisi GF, Papale M, Licari A, Chiappini E, Mulè E, et al. Allergic bronchopulmonary aspergillosis in children. Pediatr Allergy Immunol. 2020;31(S26):20-2. https://doi.org/10.1111/pai.13357
10. Rivas-Pinedo P, Oñate JM, Berrío I, Celis AM, Fernández-Suárez H, Castañeda-Luquerna X, et al. Section 1. Colombian consensus on the diagnosis and treatment of chronic, saprophytic and/or allergic syndromes associated with Aspergillus spp. in adult and pediatric patients. Infectio. 2022;26(3):262-290. https://doi.org/10.22354/24223794.1062
11. Chacko A, Moss RB. Manifestations of pulmonary aspergillosis in pediatrics. Curr Opin Pediatr. 2020;32(3):389-94.
12. Carbajo CM, Cano Aguirre MP, Pinedo C, Segrelles Calvo G, Alonso S, Girón RM. Aspergilosis broncopulmonar alérgica, diagnóstico previo de una fibrosis quística. Rev Patol Respir. 2008;11(2):84-6.
13. Calderón ALB, Múnera OLM, Pabón CLR. Aspergilosis broncopulmonar alérgica, una complicación del paciente con fibrosis quística: reporte de dos casos y revisión de la literatura. IATREIA. 2012;25(1):10.
14. Janahi I, Rehman A, Al-Naimi A. Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Ann Thorac Med. 2017;12(2):74. https://doi.org/10.4103/atm.ATM_231_16
How to Cite
Lancheros Reina, N. A., García, N., Restrepo Gualteros, S. M., & Calderón, A. F. (2023). Allergic Bronchopulmonary Aspergillosis in a Child with Cystic Fibrosis. A Case Report . Universitas Medica, 64(2). https://doi.org/10.11144/Javeriana.umed64-2.aspe
Section
Case Reports

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