Publicado oct 17, 2022



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Judith Karime Diaz Velásquez

Fredy Omar Gamboa Jaimes

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Resumen

Antecedentes: En la última década, la ingeniería tisular, la terapia celular y los avances investigativos en ciencias hematológicas se han convertido en herramientas para la odontología regenerativa, al utilizar los concentrados plaquetarios como piedra angular. Los resultados son prometedores, ante lo cual es necesario consolidar la evidencia existente sobre su real relevancia e impacto clínico. Objetivo: Realizar una revisión integradora de literatura para presentar evidencia científica referente a concentrados plaquetarios, su uso, características, beneficios y utilidad para la ingeniería tisular. Métodos: La búsqueda de información se realizó en el buscador EBSCO host, de estudios publicados entre 2010 y principios de 2020. Resultados: La mayoría de las publicaciones presenta la evolución de los concentrados plaquetarios, evalúan su uso in vitro e in vivo y comprueban clínicamente su potencial regenerativo en la reparación de tejidos blandos y óseos. Se encontraron marcadas diferencias entre, el plasma rico en plaquetas y la fibrina rica en plaquetas. Conclusión: Existe controversia y uso indiscriminado de la terminología de concentrados plaquetarios; sin embargo, ellos no sólo son una fuente de factores de crecimiento, sino también un material vivo, con base en la fibrina, cuyo posicionamiento como material quirúrgico es cada vez más evidente. Se torna en una solución de orientación tisular al optimizar la regeneración y la cicatrización, y una importante herramienta de bajo costo en la ingeniería tisular.

Keywords

dentistry, growth factors, guided regeneration, hemostasis, oral medicine, platelet concentrates, platelet-rich fibrin, platelet-rich plasma, regenerative dentistry, tissue engineering, tissue regenerationconcentrados plaquetarios, factores de crecimiento, fibrina rica en plaquetas, hemostasia, ingeniería tisular, medicina oral, odontología, odontología regenerativa, plasma rico en plaquetas, regeneración guiada, regeneración tisularconcentrados de plaquetas, engenharia de tecidos, fatores de crescimento, fibrina rica em plaquetas, hemostasia, medicina oral, odontologia, odontologia regenerativa, plasma rico em plaquetas, regeneração de tecidos, regeneração guiada

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Cómo citar
Diaz Velásquez, J. K., & Gamboa Jaimes, F. O. (2022). De la hematología a la ingeniería tisular: actualidad y proyección de los concentrados plaquetarios y sus derivados. Universitas Odontologica, 41. https://doi.org/10.11144/Javeriana.uo41.htes
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