Keywords
lipids
treatment
exercise
How to Cite
Abstract
Objective: To evaluate the impact of exercise
as a non-pharmacological intervention for
primary and secondary prevention of cardiovascular
events in people with hypercholesterolemia.
Methods: A clinical practice guideline
was developed following the guidelines of the
methodological guidance of the Ministry of
Health and Social Protection to collect systematically
the evidence and make recommendations
using the GRADE methodology. Results: Both
aerobic and resistance exercise are associated
with decreased LDL cholesterol and triglycerides,
changes were statistically significant, but
these changes are not clinically relevant since it
is a minimal reduction in these values. No statistically
significant change was found in HDL
cholesterol values. Conclusions: Recommendations
for the use of exercise as a fundamental
part of the treatment of hypercholesterolemia are
formulated. Although no clinically significant
differences in the values of cholesterol or triglycerides,
exercise is an activity with great benefits
for the patient in other clinical domains of interest,
being part of healthy lifestyles and exposure
to low risk, so when you consider the risks and
benefits of this practice, the benefits are clear and
far outweigh the low risk to which a person is
exposed when performing an exercise routine as
part of their daily lives.
Webb J, Gonnah H, Ray KK. Lipid management:
maximizing reduction of cardiac
risk. Clin Med. 2013;13:618-20.
Wachira JK, Stys TP. Cardiovascular disease
and bridging the diagnosis gap. S D
Med. 2013;66(9):366-9.
Davis B, Moriguchi T, Sumpio B. Optimizing
cardiovascular benefits of exercise:
a review of rodent models. Int J
Angiol. 2013;22:13-22.
Leosco D, Parisi V, Feminella GD,
Formisano R, Petraglia L, Alloca E, Bonaduce
D. Effects of exercise training on
cardiovascular adrenergic system. Front
Physiol. 2013;4:348.
Schuler G, Adams V, Goto Y. Role of exercise
in the prevention of cardiovascular
disease: results, mechanisms, and new perspectives.
Eur Heart J. 2013;24:1790-9.
Carrasquilla G, Pulido A, Mieth K, Muñoz
O, De la Hoz AM, Guerrero R. Guía
metodológica para la elaboración de
guías de práctica clínica con evaluación
económica en el sistema general de seguridad
social en salud colombiano. Bogotá:
Ministerio de Salud y la Protección
Social de Colombia; 2013.
Kelley GA, Kelley KS, Roberts S, et al.
Comparison of aerobic exercise, diet or
both on lipids and lipoproteins in adults:
A meta-analysis of randomized controlled
trials. Clin Nut. 2012;31:156-67.
Kelley GA, Kelley KS. Impact of progresive
resistance training on lipids and
liporpoteins in adults: A meta-analysis of
randomized controlled trials. Prev Med.
;48(1):9-19.
Tambalis K, Panagiotakos B, Kavouras
S, et al. Responses of blood lipids to
aerobic, resistance and combined aerobic
with resistance exercise training : A systematic
review of current evidence. Angiology.
;60:614-32.
Kelley GA, Kelley KS, Roberts S,
Haskell W. Efficacy of aerobic exercise
and a prudent diet for improving selected
lipids and lipoproteins in adults:
a meta-analysis of randomized controlled
trial. BMC Med. 2011;9:74. doi:
1186/1741-7015-9-74
Eckel RH, Jakicic JM, Ard JD, Miller
NH, Hubbard VS, Nonas CA, et al. 2013
AHA/ACC Guideline on lifestyle management
to reduce cardiovascular risk: a
report of the American Collegue of Cardiology
– American Heart Association
Task Force on Practice Guidelines. J Am
Coll Cardiol. 2014;63:2960-84.
Muñoz OM, García AA, Fernández D,
Higuera A, Ruiz AJ, et al. Guía de práctica
clínica para la prevención, detección
temprana, diagnóstico, tratamiento y seguimiento
de las dislipidemias en la población
mayor de 18 años. Acta Médica
Colombiana. 2014;39:s1-s28.
This journal is registered under a Creative Commons Attribution 4.0 International Public License. Thus, this work may be reproduced, distributed, and publicly shared in digital format, as long as the names of the authors and Pontificia Universidad Javeriana are acknowledged. Others are allowed to quote, adapt, transform, auto-archive, republish, and create based on this material, for any purpose (even commercial ones), provided the authorship is duly acknowledged, a link to the original work is provided, and it is specified if changes have been made. Pontificia Universidad Javeriana does not hold the rights of published works and the authors are solely responsible for the contents of their works; they keep the moral, intellectual, privacy, and publicity rights.
Approving the intervention of the work (review, copy-editing, translation, layout) and the following outreach, are granted through an use license and not through an assignment of rights. This means the journal and Pontificia Universidad Javeriana cannot be held responsible for any ethical malpractice by the authors. As a consequence of the protection granted by the use license, the journal is not required to publish recantations or modify information already published, unless the errata stems from the editorial management process. Publishing contents in this journal does not generate royalties for contributors.