Desarrollo neuroembriológico: el camino desde la proliferación hasta la perfección
Publicado
abr 29, 2019
Almetrics
Dimensions
Google Scholar
##plugins.themes.bootstrap3.article.details##
Resumen
El desarrollo neurológico humano requiere una serie de pasos que permitan orientar, regular y diferenciar los diversos componentes cerebrales, para así garantizar, de una manera bastante precisa, la correcta organización y funcionamiento de las estructuras neuronales. La neurogénesis está clásicamente dividida en cuatro etapas consecutivas: proliferación, migración, diferenciación y maduración. En los humanos,
estas ocurren desde la tercera semana de gestación hasta la vida adulta y precisan de un complejo grupo de paquetes genéticos, así como de algunos factores asociados, que se han ido descubriendo gracias a los avances en la biología molecular. El artículo es una revisión acerca del desarrollo neuroembriológico humano y los componentes genéticos más relevantes encontrados en la literatura.
Keywords
neurogenesis; embryonic and fetal development; cell migration; cell differentiation; plasticity.neurogénesis; desarrollo embrionario y fetal; migración celular; diferenciación celular; plasticidad.
References
1. Keays DA. Neuronal migration: Unraveling the molecular pathway with humans, mice, and a fungus. Mamm Genome. 2007;18:425-30.
2. Setty Y, Chen C, Secrier M, Skoblov N, Kalamatianos D, Emmott S. How neurons migrate: a dynamic in-silico model of neuronal migration in the developing cortex. BMC Syst Biol. 2011;5:154.
3. Sastre E. Alteraciones de la migración neuronal y epilepsia: Factores implicados, terapias actuales y perspectivas de futuro [Internet]. [Tesis de maestría]. Salamanca: Universidad de Salamanca; 2009. Disponible en:
http://hdl.handle.net/10366/74553.
4. Dobbing J, Sands J. Quantitative growth and development of human brain. Arch Dis Child. 1973;48:757-67.
5. Johnston M, Ishida A. Plasticity and injury in the developing brain. Brain Dev. 2009;31,1-10.
6. McQuillen P. Effects of congenital heart disease on brain development. Prog Pediatr Cardiol. 2010;29:79-85.
7. Stolp H, Neuhaus A, Sundramoorthi R, Molnár Z. The long and the short of it: Gene and
environment interactions during early cortical development and consequences for long-term neurological disease. Front. Psychiatry. 2012;3:50.
8. Stiles J, Jernigan TL. The basics of brain development. Neuropsychol Rev. 2010;20:327-48.
9. Dimecky SM, Kim JC. Molecular neuroanatomy’s “Three Gs”: A primer. Neuron. 2007;54:17-34.
10. Marsh R, Gerber AJ, Peterson BS. Neuroimaging studies of normal brain development and their relevance for understanding childhood neuropsychiatric disorders. J Am Acad Child Adolesc Psyquiatry. 2008;47:1233-51.
11. Marín O, Valiente M, Ge X, Tsai LH. Guiding neuronal cell migrations. Cold Spring Harb Perspect Biol. 2010;2:a001834.
12. Molyneaux BJ, Arlotta P, Menezes JRL, Macklis JD. Neuronal subtype specification in the cerebral cortex. Nature Rev Neurosci. 2007;8:427-37.
13. Corbin J, Gaiano N. Regulation of neural progenitor cell development in the nervous system. J. Neurochem. 2008;106:2272-87.
14. Bystron I, Blakemore C, Rakic P. Development of the human cerebral cortex: Boulder Committee revisited. Nature Rev Neurosci. 2008;9:110-22.
15. Barkovich AJ, Guerrini R, Kuzniecky RI, Jackson GD, Dobyns WB. A developmental and genetic classification for malformations of cortical development: update 2012. Brain. 2012;135:1348-69.
16. Lim HN, Van Oudenaarden A. A multistep epigenetic switch enables the stable inheritance of DNA methylation states. Nat Genet. 2007;39:269-75.
17. Rojas AE, Ortuño D. Diferenciación celular en el Sistema Nervioso, el caso de las células precursoras neuro-gliales. Rev Bio Ciencias. 2011;1:3-17.
18. Sun W, Kim H, Moon Y. Control of neuronal migration through rostral migration stream in mice. Anat Cell Biol. 2010;43:269-79.
19. Trivedi N, Solecki DJ. Neuronal migration illuminated: A look under the hood of the living neuron. Cell Adhesion, Migration. 2011;5:42-7.
20. Kawauchi T. Regulation of cell adhesion and migration in cortical neurons: Not only Rho but also Rab family small GTPases. Small GTPases. 2011;2:36-40.
21. Khodosevich K, Monyer H. Signaling in migrating neurons: from molecules to networks. Front Neurosc. 2011;5:28.
22. Hernández-Miranda LR, Parnavelas JG, Chiara F. Molecules and mechanisms involved in the generation and migration of cortical interneurons. ASN Neuro. 2010;2:e00031.
23. Yamao M, Naoki H, Ishii S. Multi-cellular logistics of collective cell migration. PloS ONE. 2011;6:e27950.
24. Govek EE, Hatten ME, Van Aelst L. The role of Rho GTPase proteins in CNS neuronal migration. Dev Neurobiol. 2012;71:528-53.
25. Sun Y, Huang Z, Yang K, Liu W, Xiw Y, Yuan B, et al. Self-organizing circuit assembly through spatiotemporally coordinated neuronal migration within geometric constraints. PloS ONE. 2011;6:e28156.
26. McCarthy DM, Sadri-Vakili G, Zhang X, Darnell SB, Sangrey GR, Yanagawa Y, et al. Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebin. J Neurosci. 2012;31:13400-11.
27. Naumburg E, Strömberg B, Kieler H. Prenatal characteristics of infants with a neuronal migration disorder: a national-based study. Int Journal Pediat. 2012:541892.
28. Chatterjee CT, Sarkar CRS, Dhot BPS, Kumar LCS, Kumar CVK. Adult stem cell plasticity: Dream or reality? Med J Armed Forces India. 2010;66:56-60.
29. Viktorin G, Chiuchitu C, Rissler M, Zoltán MV, Westerfield M. Emx3 Is Required for the Differentiation of Dorsal Telencephalic Neurons. Dev Dyn. 2009;238:1984-98.
30. Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S et al. Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects. PLoS
Genet. 2011;7:e1001331.
31. Son L, et al. Human fetal brain connectome: structural network development from middle fetal stage to birth. Front Neurosci. 2017 Oct 13;11:561
32. Sousa AMM, Meyer KA, Santpere G, Gulden FO1, Sestan N. Evolution of the human nervous system function, structure, and development. Cell. 2017 Jul 13;170(2):226-247
33. Jiang X, Nardelli J. Cellular and molecular introduction to brain development. Neurobiol Dis. 2016 Aug;92(Pt A):3-17
2. Setty Y, Chen C, Secrier M, Skoblov N, Kalamatianos D, Emmott S. How neurons migrate: a dynamic in-silico model of neuronal migration in the developing cortex. BMC Syst Biol. 2011;5:154.
3. Sastre E. Alteraciones de la migración neuronal y epilepsia: Factores implicados, terapias actuales y perspectivas de futuro [Internet]. [Tesis de maestría]. Salamanca: Universidad de Salamanca; 2009. Disponible en:
http://hdl.handle.net/10366/74553.
4. Dobbing J, Sands J. Quantitative growth and development of human brain. Arch Dis Child. 1973;48:757-67.
5. Johnston M, Ishida A. Plasticity and injury in the developing brain. Brain Dev. 2009;31,1-10.
6. McQuillen P. Effects of congenital heart disease on brain development. Prog Pediatr Cardiol. 2010;29:79-85.
7. Stolp H, Neuhaus A, Sundramoorthi R, Molnár Z. The long and the short of it: Gene and
environment interactions during early cortical development and consequences for long-term neurological disease. Front. Psychiatry. 2012;3:50.
8. Stiles J, Jernigan TL. The basics of brain development. Neuropsychol Rev. 2010;20:327-48.
9. Dimecky SM, Kim JC. Molecular neuroanatomy’s “Three Gs”: A primer. Neuron. 2007;54:17-34.
10. Marsh R, Gerber AJ, Peterson BS. Neuroimaging studies of normal brain development and their relevance for understanding childhood neuropsychiatric disorders. J Am Acad Child Adolesc Psyquiatry. 2008;47:1233-51.
11. Marín O, Valiente M, Ge X, Tsai LH. Guiding neuronal cell migrations. Cold Spring Harb Perspect Biol. 2010;2:a001834.
12. Molyneaux BJ, Arlotta P, Menezes JRL, Macklis JD. Neuronal subtype specification in the cerebral cortex. Nature Rev Neurosci. 2007;8:427-37.
13. Corbin J, Gaiano N. Regulation of neural progenitor cell development in the nervous system. J. Neurochem. 2008;106:2272-87.
14. Bystron I, Blakemore C, Rakic P. Development of the human cerebral cortex: Boulder Committee revisited. Nature Rev Neurosci. 2008;9:110-22.
15. Barkovich AJ, Guerrini R, Kuzniecky RI, Jackson GD, Dobyns WB. A developmental and genetic classification for malformations of cortical development: update 2012. Brain. 2012;135:1348-69.
16. Lim HN, Van Oudenaarden A. A multistep epigenetic switch enables the stable inheritance of DNA methylation states. Nat Genet. 2007;39:269-75.
17. Rojas AE, Ortuño D. Diferenciación celular en el Sistema Nervioso, el caso de las células precursoras neuro-gliales. Rev Bio Ciencias. 2011;1:3-17.
18. Sun W, Kim H, Moon Y. Control of neuronal migration through rostral migration stream in mice. Anat Cell Biol. 2010;43:269-79.
19. Trivedi N, Solecki DJ. Neuronal migration illuminated: A look under the hood of the living neuron. Cell Adhesion, Migration. 2011;5:42-7.
20. Kawauchi T. Regulation of cell adhesion and migration in cortical neurons: Not only Rho but also Rab family small GTPases. Small GTPases. 2011;2:36-40.
21. Khodosevich K, Monyer H. Signaling in migrating neurons: from molecules to networks. Front Neurosc. 2011;5:28.
22. Hernández-Miranda LR, Parnavelas JG, Chiara F. Molecules and mechanisms involved in the generation and migration of cortical interneurons. ASN Neuro. 2010;2:e00031.
23. Yamao M, Naoki H, Ishii S. Multi-cellular logistics of collective cell migration. PloS ONE. 2011;6:e27950.
24. Govek EE, Hatten ME, Van Aelst L. The role of Rho GTPase proteins in CNS neuronal migration. Dev Neurobiol. 2012;71:528-53.
25. Sun Y, Huang Z, Yang K, Liu W, Xiw Y, Yuan B, et al. Self-organizing circuit assembly through spatiotemporally coordinated neuronal migration within geometric constraints. PloS ONE. 2011;6:e28156.
26. McCarthy DM, Sadri-Vakili G, Zhang X, Darnell SB, Sangrey GR, Yanagawa Y, et al. Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebin. J Neurosci. 2012;31:13400-11.
27. Naumburg E, Strömberg B, Kieler H. Prenatal characteristics of infants with a neuronal migration disorder: a national-based study. Int Journal Pediat. 2012:541892.
28. Chatterjee CT, Sarkar CRS, Dhot BPS, Kumar LCS, Kumar CVK. Adult stem cell plasticity: Dream or reality? Med J Armed Forces India. 2010;66:56-60.
29. Viktorin G, Chiuchitu C, Rissler M, Zoltán MV, Westerfield M. Emx3 Is Required for the Differentiation of Dorsal Telencephalic Neurons. Dev Dyn. 2009;238:1984-98.
30. Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S et al. Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects. PLoS
Genet. 2011;7:e1001331.
31. Son L, et al. Human fetal brain connectome: structural network development from middle fetal stage to birth. Front Neurosci. 2017 Oct 13;11:561
32. Sousa AMM, Meyer KA, Santpere G, Gulden FO1, Sestan N. Evolution of the human nervous system function, structure, and development. Cell. 2017 Jul 13;170(2):226-247
33. Jiang X, Nardelli J. Cellular and molecular introduction to brain development. Neurobiol Dis. 2016 Aug;92(Pt A):3-17
Cómo citar
Herández Flórez, C. E., Contreras García, G. A., & Beltrán Avendaño, M. A. (2019). Desarrollo neuroembriológico: el camino desde la proliferación hasta la perfección. Universitas Medica, 59(3), 1–10. https://doi.org/10.11144/Javeriana.umed59-3.dneu
Número
Sección
Revisión de tema