Keywords
Epstein-Barr virus
radiotherapy
lethal midline granuloma
How to Cite
Abstract
The nasal natural killer T-cell lymphoma, also known as lethal midline granuloma, is an uncommon entity. It consists of an extranodal lymphoma of aggressive behavior that generally arises from de nasal cavity. Ii is prevalent in eastern countries and in males in the third decade. Epstein-Barr virus infection in association with this lymphoma is well documented. Current practice is in favor of radiotherapy.
We present a case report, and a review of the literature of nasal natural killer T-cell lymphoma was done as an initiative to provide a better understanding of this pathology.
Borges A, Fink J, Villablanca P, et al. Midline destructive lesions of the
sinonasal tract: Simplified terminology based on histopathologic criteria. AJNR Am J Neuroradiol. 2000;21:331-6.
Savage KJ, Chhanabhai M, Gascoyne RD, et al. Characterization of peripheral T-cell lymphomas in a single North American institution by the WHO classification. Ann Oncol. 2004; 15:1467-75.
Mishima K, Horiuchi K, Kojya S, et al. Epstein-Barr virus in patients with polymorphic reticulosis (lethal midline granuloma) from China and Japan. Cancer. 1994;73:3041-6.
Aozasa K, Yang WI, Lee YB, et al. Lethal midline granuloma in Seoul
(Korea) and Shanghai (China). Int J Cancer. 1992;52:673-4.
Smalley SR, Cupps RE, Anderson JA, et al. Polymorphic reticulosis limited to the upper aerodigestive tract: Natural history and radiotherapeutic considerations. Int J Radiat Oncol Biol Phys. 1988;15:599-605.
Lipford EH Jr, Margolick JB, Longo DL, et al. Angiocentric immunoproliferative lesions: A clinicopathologic spectrum of post-thymic T-cell proliferations. Blood. 1988;72:1674-81.
Gaal K, Sun NC, Hernández AM, Arber DA. Sinonasal NK/T-cell lymphomas in the United States. Am J Surg Pathol. 2000;24:1511-7.
Daihachiro S, Kazuyoshi U, Yuichi K, Yoshito E. Clinicopathological features of Epstein–Barr virus-associated nasal T:NK cell lymphomas in southern Japan. Auris Nasus Larynx. 2001; 28:61-70.
Sakata K, Hareyama M, Ohuchi A, et al. Treatment of lethal midline granuloma type nasal T-cell lymphoma. Acta Oncol. 1997;36:307-11.
Wei Y, Jeffery C. Stewart, Kratochvil J, Zieper M. Angiocentric T-cell
lymphoma presenting as midface destructive lesion: Case report and
literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.
;94:353-60.
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