Keywords
bone development
prenatal diagnosis
How to Cite
Abstract
Objective: Our aim was to conduct an analysis of risk factors from a population with skeletal dysplasia notified in some cities of Colombia in the last eight years. Methods: We conducted a case-control study in several Colombian hospitals participating in the Latin-American Collaborative Study of Congenital Malformations (ECLAMC, Spanish acronym). For the analysis 29 cases and 85 controls were included.
Results: In the quantitative variables we found statistical significance between cases and controls for paternal age, gestational age, number of gestations and birth weight. With regard to qualitative variables, the cases had a higher risk of birth weight less than 2500 g and low birth weight for the gestational age.
Conclusions: Skeletal dysplasias are a congenital malformation with a low frequency in the population studied and often lacking of a specific diagnostic. They are associated with advanced paternal age, low birth weight, gestational age and number of gestations.
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