Desenlaces tempranos del manejo de la asfixia perinatal con Cool-cap y Manta

Abstract

Introduction: Short-term results obtained with body cooling using Cool-cap®️ and blanket are controversial. The outcomes of the two intervention modalities are presented under the same protocol and institution. Patients and methods: ambidirectional cohort study of newborns with moderate or severe perinatal asphyxia treated with controlled hypothermia between 2018 and 2020 in a hospital in Bogotá, Colombia Results: 164 patients received therapeutic hypothermia with the mentioned devices (Cool-cap®️ 54,2 %; Manta 45,7%). Mortality was 11,2% and 16% respectively, with a higher proportion of patientes with sarnat III in the latter group (16 % vs. 6 %). The Cool-cap®️ group presented more cardiovascular disorders (60 %); pulmonary hypertension and hematological disorders had a similar proportion in both groups. In both interventions, more than half of the patients were admitted outside therapeutic window period and had an overall mortality of 14,8 % (Cool-cap®️ n=7 and blanket n=7) Conclusions: overall mortality was 13,4%, lower than the one reported in literature, which varies between 14% and 20%, despite the fact thar more than half of the patients were admitted outside the therapeutic window period. This being greater in the blanket group, a difference that is explained by the disparity in the distribution of the prognostic factors at admission of both groups.