Published Nov 28, 2010



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Tatiana Roldán

Óscar Zorro

Luis María Villalobos

Lina María Rodríguez

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Abstract

Primary central nervous system lymphoma is a rare condition which commonly presents in immunosuppressed patients.

We present the case of a 38 year old female with no relevant previous medical history who underwent surgery for the removal of a mass located in her left cerebello pontine angle. Final pathology report was consistent with B – cell lymphoma (large cell variant). A survey for hidden conditions which could predispose the patient to immunodeficiency was negative. The age of presentation for this case was also atypical. Further genetic and molecular testing could provide a possible explanation for this rare event.

Keywords

linfoma primario, ángulo pontocerebeloso, sistema nervioso central, primary lymphoma, cerebellopontine angle, central nervous system,

References
1. Engels E, Biggar R, Hall H, Cross H, Crutchfield A, Finch J, Grigg R, Hylton T, Pawlish K, McNeel T, Goedert J. Cancer risk in people infected with human immunodeficiency virus in the United. Int J Cancer. 2008;123:187-94.
2. Chimienti E, Spina M, Vaccher E, Tirelli U. Management of immunocompetent patients with primary central nervous system lymphoma. Clin Lymphoma Myeloma. 2009;5:353-64.
3. Batchelor T, Loeffler JS. Primary CNS lymphoma. J Clin Oncol. 2006;24:1281-8.
4. Rubenstein J, Ferreri A, Pitaluga S. Primary lymphoma of the central
nervous system: Epidemiology, pathology and current approaches to
diagnosis, prognosis and treatment. Leuk Lymphoma. 2008;49(Suppl.1):43-51.
5. Olson JE, Janney CA, Rao RD, Cerhan JR, Kurtin PJ, Schiff D, et al. The
continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: A surveillance, epidemiology, and end results analysis. Cancer. 2002;95:1504-10.
6. Mohile N, Abrey L. Primary central nervous system lymphoma. Neurol
Clin. 2007;25:1193-207.
7. van der Valk P. Central nervous system lymphomas. Curr Diagn Pathol. 1996; 3:45-52.
8. Jahnke K, Hummel M, Korfel A, Burmeister T, Kiewe P, Klasen HA,
Müller HH, Stein H, Thiel E.. Detection of subclinical systemic disease in
primary CNS lymphoma by polymerase chain reaction of the rearranged immunoglobulin heavy chain genes. J Clin Oncol. 2006;24:4754-7.
9. Koga H, Zhang S, Ichikawa T, Washiyama K, Kuroiwa T, Tanaka R,
Kumanishi T. Primary malignant lymphoma of the brain: Demonstration
of the p53 gene mutations by PCRSSCP analysis and immunohistochemistry. Brain Tumor Pathol. 1994;11:151-5.
10. Ferreri AJ, Reni M, Pasini F, Calderoni A, Tirelli U, Pivnik A, et al. A
multicenter study of treatment of primary CNS lymphoma. Neurology.
2002;58:1513-20.
11. Ferreri AJ, Abrey LE, Blay JY, Borisch B, Hochman J, Neuwelt EA, et al. Summary statement on primary central nervous system lymphomas from the Eighth International Conference on Malignant Lymphoma, Lugano, Switzerland, June 12 to 15, 2002. J Clin Oncol. 2003;21:2407-14.
12. Abrey L, Yahalom J, De Angelis L. Treatment for primary CNS lymphoma: The next step. J Clin Oncol. 2000; 18:3144-50.
How to Cite
Roldán, T., Zorro, Óscar, Villalobos, L. M., & Rodríguez, L. M. (2010). Primary central nervous system lymphoma of posterior fossa in young patient. Universitas Medica, 52(1), 112–119. https://doi.org/10.11144/Javeriana.umed52-1.lpsn
Section
Case Reports

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