Leucemia linfoide aguda B biclonal en un paciente pediátrico: reporte de caso en el servicio de Oncopediatría del Hospital Universitario San Ignacio

Alba Myriam Campos Arenas; Korin Stefania Rios; Laura Rey; iliana De Los Reyes; Paula Carolina Guzmán Cruz; Niyireth Peñaloza Castañeda; Sandra Milena Quijano Gómez

doi:10.11144/Javeriana.umed61-1.bicl

Published Dec 16, 2019

DOI https://doi.org/10.11144/Javeriana.umed61-1.bicl

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Alba Myriam Campos Arenas

Hospital Universitario San Ignacio, Laboratorio Clínico, Área de Citometría de Flujo. Grupo Ciencias del Laboratorio

https://orcid.org/0000-0002-8405-9311

Korin Stefania Rios

Laboratorios Bienestar IPS

https://orcid.org/0000-0002-7732-3444

Laura Rey

Grupo de investigación en Biología del Cáncer, Instituto Nacional de Cancerología - E.S.E. Bogotá, Colombia "

https://orcid.org/0000-0002-0706-2162

iliana De Los Reyes

Fundación SantaFe de Bogotá

https://orcid.org/0000-0002-1011-1068

Paula Carolina Guzmán Cruz

International Society of Pediatric Oncology (SIOP)

https://orcid.org/0000-0002-6615-7161

Niyireth Peñaloza Castañeda

Hospital Universitario San Ignacio

https://orcid.org/0000-0003-4999-8193

Sandra Milena Quijano Gómez

Hospital Universitario San Ignacio

https://orcid.org/0000-0003-4452-9291

Abstract

This is a paediatric patient diagnosed with acute lymphoblastic leukaemia (ALL) of B precursors, with two populations of different blasts characterized by flow cytometry (one population has an immunophenotype associated with Pre-B cells and another population corresponds to B-ALL). The genetic analysis in the bone marrow reported the presence of t (9; 22) (q34; q11) with BCR-ABL, DNA hyperdiploidy (> 50 chromosomes) and trisomy of chromosome 5. Given the genetic complexity, the patient was controlled weekly by flow cytometry with persistence of the tumor population corresponding to the common ALL-B, until its final remission.

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Campos Arenas, A. M., Rios, K. S., Rey, L., De Los Reyes, iliana, Guzmán Cruz, P. C., Peñaloza Castañeda, N., & Quijano Gómez, S. M. (2019). Acute B-cell Lymphoblastic Leukemia in a Pediatric Patient: Case Report in the Pediatric Oncopediatrics Service of Hospital Universitario San Ignacio. Universitas Medica, 61(1). https://doi.org/10.11144/Javeriana.umed61-1.bicl

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Vol. 61 No. 1 (2020)

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Case Reports

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