Uso de anticuerpo monoclonal para tratamiento de osteonecrosis de talo y cabeza humeral bilaterales secundario al uso de corticoides por leucemia linfoide aguda. Reporte de caso
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Palavras-chave

osteonecrosis
leucemia linfoide aguda
tratamiento
bisfosfonato
anticuerpo monoclonal

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Uso de anticuerpo monoclonal para tratamiento de osteonecrosis de talo y cabeza humeral bilaterales secundario al uso de corticoides por leucemia linfoide aguda. Reporte de caso. (2014). Universitas Medica, 56(1), 110-118. https://revistas.javeriana.edu.co/index.php/vnimedica/article/view/16347
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Resumo

La osteonecrosis es una causa de dolor articular y deformidad, generalmente, causada por trauma. La osteonecrosis no traumática es otra forma de presentación de dicha patología y mayormente asociada al uso de corticoides. Se hizo una revisión de la literatura en cuanto al manejo de los pacientes en quienes cursa dicha patología, en los que se evidencian manejo conservadores dados por seguimiento, inmovilización o manejos quirúrgicos, como core decompresion, reemplazos articulares o artrodesis. En muy pocos artículos se encuentra evidencia de manejo con bisfosfonatos, en especial con ácido ibandrónico, para el manejo sintomático de dicha patología secundaria al uso de corticoide en pacientes con leucemia linfoide aguda. No hay reportes en la literatura acerca del uso de anticuerpos monoclonales para el manejo de pacientes con osteonecrosis, utilizados en mujeres con osteoporosis inducida por menopausia.

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Brooker BJ, Keith PPA. Osteonecrosis: The perils of steroids. A review of the literature and case report. Case Reports in Clinical Medicine. 2012;1(2):26-37.

Padhye B, Dalla-Pozza L, Little D, Munns C. Use of zoledronic acid for treatment of chemotherapy related osteonecrosis in children and adolescents: A retrospective analysis. Pediatr Blood Cancer. 2013;60:1539-45.

Saini A, Saifuddin A. MRI of osteonecrosis. Clin Radiol. 2004;59:1079-93.

Murphy RG, Greenberg ML. Osteonecrosis in pediatric patients with acute lymphoblastic leukemia. Cancer. 1990;65:1717-21.

Solarino G, Scialpi L, Bruno N, De Cillis B. On a case of multifocal osteonecrosis in a patient suffering from acute lymphoblastic leukemia. Chir Organi Mov. 2008;92:119-22.

Mont MA, LaPorte D, Jones LC. Symptomatic multifocal osteonecrosis: A multicenter study. Collaborative Osteonecrosis Group. Clin Orthop Relat Res. 1999;369:312-26.

Mattano LA Jr, Sather HN, Trigg ME, Nachman JB. Osteonecrosis as a complication of trating acute lymphoblastic leukemia in children: A report from the Children´s Cancer Group. J Clin Oncol. 2000;18:3262-72.

Mont MA, Jones LC, Hungerford DS. Nontraumatic osteonecrosis of the femoral head: Ten years later. J Bone Joint Surg. 2006;88:1117-32.

Atsumi T, Kuroki Y. Role of impairment of blood supply of the femoral head in the pathogenesis of idiopathic osteonecrosis. Clin Orthop Relat Res. 1992;277:22-30.

Sala A, Mattano LA Jr, Barr RD. Osteonecrosis in children and adolescents with cancer-An adverse effect of systemic therapy. Eur J Cancer. 2007;43:683-9.

Ojala AE, Paakko E, Lanning FP, Lanning M. Osteonecrosis during the treatment of childhood acute lymphoblastic leukemia: A prospective MRI study. Med Pediatr Oncol. 1999;32:11-7.

Aricò M, Boccalatte MF, Silvestri D et al. Osteonecrosis: An emerging complication of intensive chemotherapy for childhood acute lymphoblastic leukemia. Haematologica. 2003;88:747-53.

Wei SY, Esmail AN, Bunin N, Dormans JP. Avascular necrosis in children with acute lymphoblastic leukemia. J Pediatr Orthop. 2000;20:331-5.

Raab P, Kuhl J, Krauspe R. Multifocal osteonecrosis in children and adolescents after polychemotherapy. Z Orthop Ihre Grenzgeb. 1997;135:444-50.

Silverman SL. Bisphosphonate use in conditions other than osteoporosis. Ann NY Acad Sci. 2011;1218:33-7.

Weinstein RS. Glucocorticoid-induced osteoporosis and osteonecrosis. Endocrinol Metab Clin North Am. 2012;41(3):595-611.

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