Publicado sep 21, 2022



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Ana María Zarante Bahamón https://orcid.org/0000-0002-2244-0838

Sandra Navarro Marroquin https://orcid.org/0000-0002-1919-8972

Fernando Suárez-Obando https://orcid.org/0000-0001-6336-5347

Jorge Ramón Gomez https://orcid.org/0000-0002-2697-2380

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Resumen

La hiperamonemia se define como el aumento de las concentraciones de amonio en el plasma, de forma aguda o crónica. Frecuentemente, se presenta en diversos tipos de errores innatos del metabolismo, enfermedades que deben diagnosticarse y manejarse de manera inmediata y adecuada, debido a que el retraso en su manejo genera secuelas neurológicas graves y permanentes, así como desenlaces fatales. El objetivo del artículo es aportar herramientas al clínico para la sospecha, el abordaje diagnóstico y el manejo del recién nacido con hiperamonemia primaria, teniendo en cuenta la correlación entre fisiopatología, etiología, aproximación clínica y de laboratorio, así como recomendaciones de manejo farmacológico y no farmacológico.

Keywords

hiperamonemia, coma, encefalopatia, error innato del metabolismo, recien nacido

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Cómo citar
Zarante Bahamón, A. M., Navarro Marroquin, S., Suarez-Obando, F., & Ramón Gómez, J. L. (2022). Recomendaciones de manejo de la hiperamonemia en neonatos. Universitas Medica, 63(4). https://doi.org/10.11144/Javeriana.umed63-4.rmhn
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