Published Aug 30, 2013



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Gabriel Alonso Mosquera Klinger

Fernando Vela Lozada

Carlos Álvarez Moreno

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Abstract

Leptospirosis is an acute generalized infectious disease, produced by spirochetes Leptospira, caracterized by an extensive vasculitis. Should always be considered in the differential diagnosis of febrile syndrome in our population. We report a series of 14 cases with symptoms indicative of leptospirosis, which showed positive serology for Leptospira spp., confirming the diagnosis. Demographic characteristics are described in our population was more common in people between 20 and 35 years. In 35.7% there was a history of recent travel to northern municipalities in Tolima department, and in 14.2% to municipalities in southern Cundinamarca. 71.4% of patients had risk factors for infection. Most emergency room visits occurred seven days after the onset of symptoms in all patients appear fever, headache, myalgia, and arthralgia, to a lesser extent diarrhea and abdominal pain.

Keywords

Leptospirosis, febrile syndrome, jaundice, zoonosis, leptospirosis, síndrome febril, ictericia, zoonosis,

References
1. Organización Mundial de la Salud, Organización Panamericana de la Salud (OMS/OPS). Definiciones de caso: dengue y leptospirosis. Boletín Epidemiológico OMS/OPS. 2000;21:14-5.
2. Daher E, Lima R, Junior GS, et al. Clinical presentation of leptospirosis: A retrospective study of 201 patients in a metropolitan city of Brazil. Braz J Infect Dis. 2010;14:3-10.
3. Zunino E, Pizarro R. Leptospirosis: puesta al día. Rev Chil Infect. 2007;24: 220-6.
4. Levett PN. Leptospira. En: Murray P, Baron E, Jorgensen J, Landry M, Pfaller M, editors. Manual of clinical microbiology. 9th ed. Washington: ASM; 2007. p. 963-70.
5. Levett P. Leptospirosis. Clin Microbiol Rev. 2001;14:296-326.
6. Céspedes M. Leptospirosis: enfermedad zoonótica reemergente. Rev Peru Med Exp Salud Pública. 2005;22:290-307.
7. Góngora A, Parra J, Aponte L. Seroprevalence of Leptospira spp. in population groups of Villavicencio, Colombia. Rev Salud Pública. 2008;10:269-78.
8. Macías J, Vergara C, Romero C, Falconar AKI. Comportamiento de la leptospirosis en el departamento del Atlántico (Colombia), enero de 1999 a marzo de 2004. Salud Uninorte Barranquilla (Colombia). 2005;20:18-29.
9. Agudelo-Flórez P. Leptospirosis humana en Colombia: la experiencia del Instituto Colombiano de Medicina Tropical-CES. Revista CES Medicina. 2007;21(Supl. 1):55-8.
10. Sarkar J, Chopra A, Katageri B, Hansraj, Goel A. Leptospirosis: a re-emerging infection. Asian Pac J Trop Med. 2012; 5(6):500-2.
11. Lau C, Smythe L, Weinstein P. Leptospirosis: An emerging disease in travellers. Travel Med Infect Dis. 2010;8:33-9.
12. Panaphut T, Domrongkitchaiporn S, Vibhagool A, Thinkamrop B, Susaengrat W. Ceftriaxone compared with sodium penicillin G for treatment of severe leptospirosis. Clin Infect Dis. 2003;36: 1507-13.
13. Yang HY, Yen TH, Lin CY, et al. Early identification of leptospirosis as an ignored cause of multiple organ dysfunction síndrome. Shock. 2012;38(1):24-9.
14. Shenoy VV, Nagar VS, Chowdhury AA, Bhalgat PS, Juvale NI. Pulmonary leptospirosis: an excellent response to bolus methylprednisolone. Postgrad Med J. 2006;82(971):602-6.
15. Wagenaar JF, Goris MG, Partiningrum DL, et al. Coagulation disorders in patients with severe leptospirosis are associated with severe bleeding and mortality. Trop Med Int Health. 2010; 15(2):152-9.
16. Meaudre E, Asencio Y, Montcriol A, et al. Immunomodulation in severe leptospirosis with multiple organ failure: plasma exchange, intravenous immunoglobulin or corticosteroids? Ann Fr Anesth Reanim. 2008;27(2):172-6.
How to Cite
Mosquera Klinger, G. A., Vela Lozada, F., & Álvarez Moreno, C. (2013). Report of 14 cases of Leptospirosis in a 4th-Level University Hospital from 2010 to 2012. Universitas Medica, 55(1), 93–100. https://doi.org/10.11144/Javeriana.umed55-1.umbc
Section
Case Reports

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