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Objective: To establish the serum levels of folic acid in a group of adult patients. Methods: Measurement of folic acid using immunoassay in 1797 subjects. Measures of central tendency and 95% CI were calculated. Age groups and genders were compared with non-parametric tests. Results: The overall mean serum folate was: 11.61 ng/ml (SD: 6.05). The average for women was: 11.87 ng/ml (SD: 6.09). The average for men was: 11.31 ng/ml (SD: 6). Percentiles 5, 50, and 95 by sex and age are reported. In 2% of cases folic acid was found < 2 ng/ml (2% of men and 3% women). Discussion: Serum levels of folic acid are higher in women than in men (p=0.024), which contrasts with the notion of micronutrient deficiency in females. Conclusions: The presented measurements are an appropriate comparator described for measurements in general population samples.
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