Abstract
Osteosarcoma is a malignant bone primary tumour characterized for osteoid synthesis produced by malignant osteoblasts. Evidence of osteoid formation by neoplastic cells is considered an essential criterion for diagnosis and microscopic evidence of neoplastic bone, even if minimal, confirms the diagnosis. The jawbone is considered to be the most common site in the head and neck region. Maxillary swelling and pain associated tooth mobility is the most common clinical manifestation and radiographically presented as a mixed osteolytic lesion, or osteoblastic. Histopathologically it is characterized by the formation of osteoid. This article presents the case of a woman of 45 years old, diagnosed with low-grade fibroblast osteosarcoma. Given the rarity of the tumor, we present a case report and literature review, which represents an important contribution to a better understanding of the maxillary osteosarcomas is made.
Tabatabaei SH, Jahanshahi G, Marvasti
FD. Diagnostic challenges of low-grade
central osteosarcoma of jaw: A literature
review. J Dentistry. 2015;16(2):62
Guérin M, Thariat J, Ouali M, Bouvier
C, Decouvelaere AV, Cassagnau E, Larousserie
F, et el. A new subtype of highgrade
mandibular osteosarcoma with
RASAL1/MDM2 amplification. Hum
Pathol. 2016;50:70-8. doi: 10.1016/j.
humpath.2015.11.012
Tan JZ, Schlicht SM, Powell GJ, Thomas
D, Slavin JL, Smith PJ, et al. Multidisciplinary
approach to diagnosis and management
of osteosarcoma: A review of
the St Vincent’s Hospital experience. Int
Semin Surg Oncol. 2006;3:38.
Chakravarthi PS, Kattimani VS, Prasad
LK, Satish PR. Juxtacortical osteosarcoma
of the mandible: Challenges in diagnosis
and management. Nat J Maxillofac
Surg. 2015;6(1):127.
Granowski-LeCornu M, Chuang SK,
Kaban LB, August M. Osteosarcoma of
the jaws: Factors influencing prognosis. J
Oral Maxillof acSurg. 2011; 69(9):2368-
Thariat J, Julieron M, Brouchet A, Italiano
A, Schouman T, Marcy PY, Miller R.
Osteosarcomas of the mandible: are they
different from other tumor sites. Crit Revi
Oncol Hemathol. 2012;82(3):280-95.
Wang GD, Zhao YF, Liu Y, Jiang L,
Jiang XZ. Periosteal osteosarcoma of
the mandible: case report and review of
the literature. J Oral Maxillofac Surg.
;69(6):1831.
Samraj L, Kaliamoorthy S, Venkatapathy
R, Oza N. Osteosarcoma of the mandible:
A case report with an early radiographic
manifestation. Imaging Sci Dent.
;44(1):85-8.
Sturgis EM, Potter BO. Sarcomas of the
head and neck region. Curr Opin Oncol.
;15:239.
Weinfeld MS, Dudley HR. Osteogenic
sarcoma. J Bone Joint Surg Am.
;44(2):269-76.
Khorate MM, Goel S, Singh MP, Ahmed
J. Osteosarcoma of mandible: a case report
and review of literature. J Cancer Sci
Ther. 2010;2:122-5. doi:10.4172/1948-
1000036
This journal is registered under a Creative Commons Attribution 4.0 International Public License. Thus, this work may be reproduced, distributed, and publicly shared in digital format, as long as the names of the authors and Pontificia Universidad Javeriana are acknowledged. Others are allowed to quote, adapt, transform, auto-archive, republish, and create based on this material, for any purpose (even commercial ones), provided the authorship is duly acknowledged, a link to the original work is provided, and it is specified if changes have been made. Pontificia Universidad Javeriana does not hold the rights of published works and the authors are solely responsible for the contents of their works; they keep the moral, intellectual, privacy, and publicity rights.
Approving the intervention of the work (review, copy-editing, translation, layout) and the following outreach, are granted through an use license and not through an assignment of rights. This means the journal and Pontificia Universidad Javeriana cannot be held responsible for any ethical malpractice by the authors. As a consequence of the protection granted by the use license, the journal is not required to publish recantations or modify information already published, unless the errata stems from the editorial management process. Publishing contents in this journal does not generate royalties for contributors.