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Abstract
This is a paediatric patient diagnosed with acute lymphoblastic leukaemia (ALL) of B precursors, with two populations of different blasts characterized by flow cytometry (one population has an immunophenotype associated with Pre-B cells and another population corresponds to B-ALL). The genetic analysis in the bone marrow reported the presence of t (9; 22) (q34; q11) with BCR-ABL, DNA hyperdiploidy (> 50 chromosomes) and trisomy of chromosome 5. Given the genetic complexity, the patient was controlled weekly by flow cytometry with persistence of the tumor population corresponding to the common ALL-B, until its final remission.
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