Keywords
cerebellopontine angle
central nervous system
How to Cite
Abstract
Primary central nervous system lymphoma is a rare condition which commonly presents in immunosuppressed patients.
We present the case of a 38 year old female with no relevant previous medical history who underwent surgery for the removal of a mass located in her left cerebello pontine angle. Final pathology report was consistent with B – cell lymphoma (large cell variant). A survey for hidden conditions which could predispose the patient to immunodeficiency was negative. The age of presentation for this case was also atypical. Further genetic and molecular testing could provide a possible explanation for this rare event.
Engels E, Biggar R, Hall H, Cross H, Crutchfield A, Finch J, Grigg R, Hylton T, Pawlish K, McNeel T, Goedert J. Cancer risk in people infected with human immunodeficiency virus in the United. Int J Cancer. 2008;123:187-94.
Chimienti E, Spina M, Vaccher E, Tirelli U. Management of immunocompetent patients with primary central nervous system lymphoma. Clin Lymphoma Myeloma. 2009;5:353-64.
Batchelor T, Loeffler JS. Primary CNS lymphoma. J Clin Oncol. 2006;24:1281-8.
Rubenstein J, Ferreri A, Pitaluga S. Primary lymphoma of the central
nervous system: Epidemiology, pathology and current approaches to
diagnosis, prognosis and treatment. Leuk Lymphoma. 2008;49(Suppl.1):43-51.
Olson JE, Janney CA, Rao RD, Cerhan JR, Kurtin PJ, Schiff D, et al. The
continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: A surveillance, epidemiology, and end results analysis. Cancer. 2002;95:1504-10.
Mohile N, Abrey L. Primary central nervous system lymphoma. Neurol
Clin. 2007;25:1193-207.
van der Valk P. Central nervous system lymphomas. Curr Diagn Pathol. 1996; 3:45-52.
Jahnke K, Hummel M, Korfel A, Burmeister T, Kiewe P, Klasen HA,
Müller HH, Stein H, Thiel E.. Detection of subclinical systemic disease in
primary CNS lymphoma by polymerase chain reaction of the rearranged immunoglobulin heavy chain genes. J Clin Oncol. 2006;24:4754-7.
Koga H, Zhang S, Ichikawa T, Washiyama K, Kuroiwa T, Tanaka R,
Kumanishi T. Primary malignant lymphoma of the brain: Demonstration
of the p53 gene mutations by PCRSSCP analysis and immunohistochemistry. Brain Tumor Pathol. 1994;11:151-5.
Ferreri AJ, Reni M, Pasini F, Calderoni A, Tirelli U, Pivnik A, et al. A
multicenter study of treatment of primary CNS lymphoma. Neurology.
;58:1513-20.
Ferreri AJ, Abrey LE, Blay JY, Borisch B, Hochman J, Neuwelt EA, et al. Summary statement on primary central nervous system lymphomas from the Eighth International Conference on Malignant Lymphoma, Lugano, Switzerland, June 12 to 15, 2002. J Clin Oncol. 2003;21:2407-14.
Abrey L, Yahalom J, De Angelis L. Treatment for primary CNS lymphoma: The next step. J Clin Oncol. 2000; 18:3144-50.
This journal is registered under a Creative Commons Attribution 4.0 International Public License. Thus, this work may be reproduced, distributed, and publicly shared in digital format, as long as the names of the authors and Pontificia Universidad Javeriana are acknowledged. Others are allowed to quote, adapt, transform, auto-archive, republish, and create based on this material, for any purpose (even commercial ones), provided the authorship is duly acknowledged, a link to the original work is provided, and it is specified if changes have been made. Pontificia Universidad Javeriana does not hold the rights of published works and the authors are solely responsible for the contents of their works; they keep the moral, intellectual, privacy, and publicity rights.
Approving the intervention of the work (review, copy-editing, translation, layout) and the following outreach, are granted through an use license and not through an assignment of rights. This means the journal and Pontificia Universidad Javeriana cannot be held responsible for any ethical malpractice by the authors. As a consequence of the protection granted by the use license, the journal is not required to publish recantations or modify information already published, unless the errata stems from the editorial management process. Publishing contents in this journal does not generate royalties for contributors.