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Objective: To determinate risk factors associated to neonatal hypoglycemia in healthy newborns. Materials and methods: Case-control study nested in a retrospective cohort. Logistic regression analysis. Results: 40 cases and 40 controls were evaluated. The main risk factors according to the literature were reported. Skin to skin care was found as an isolated protective factor to develop neonatal hypoglycemia, although, the regression logistic analysis showed, that only the need to enhance feeding with formula was a risk factor to develop neonatal hypoglycemia (OR=9). Conclusion: Inadequate exclusive breastfeeding remains the major risk factor for transient neonatal hypoglycaemia in healthy term newborn, leading to increased use of formula
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