Metastatic Brainstem Glioma in Children: A Case Report and Review
Published
Aug 16, 2012
Almetrics
Dimensions
Google Scholar
##plugins.themes.bootstrap3.article.details##
Abstract
This article presents a 33 months old patient, with failure to thrive, alterations in gait and swallow. Brain and spine magnetic resonance showed masses at medulla and pons, venous thrombosis in the left transverse sinus and metastatic masses to spinal cord. Unresectable metastatic brainstem glioma was diagnosed. Oncology started treatment with chemotherapy and radiotherapy having a survival time of more than 3 years.
Keywords
Glioma, brainstem, medulla oblongata, diagnosis, glioma, tallo cerebral, bulbo raquídeo, diagnóstico,
References
1. Lanskowsky P. Central nervous system malignancies. En: Manual of pediatric hematology and oncology. 4th ed. New York: Elsevier; 2005. p. 513-29.
2. Saran F. Recent advances in paediatric neuro-oncology. Curr Opin Neurol. 2002 Dic;15(6):671-7.
3. Hargrave D. Paediatric high and low grade glioma: the impact of tumour biology on current and future therapy. Br J Neurosurg. 2009 Ago;23(4):351-63.
4. Qaddoumi I, Sultan I, Broniscer A. Pediatric low-grade gliomas and the need for new options for therapy: Why and how? Cancer Biol Ther. 2009 Ene;8(1):4-10.
5. Massimino M, Spreafico F, Cefalo G et al. High response rate to cisplatin/etoposide regimen in childhood low-grade glioma. J Clin Oncol. 2002 Oct 15;20(20):4209-16.
6. Kuo DJ, Weiner HL, Wisoff J, Miller DC et al. Temozolomide is active in childhood, progressive, unresectable, lowgrade gliomas. J Pediatr Hematol Oncol. 2003 May;25(5):372-8.
7. Rutka JT, Kuo JS. Pediatric surgical neuro-oncology: current best care practices and strategies. J Neurooncol. 2004 Ago-Sep;69(1-3):139-50.
8. Lashford LS, Thiesse P, Jouvet A et al. A United Kingdom Children‘s Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. Temozolomide in malignant gliomas of childhood: a United Kingdom Children‘s Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. J Clin Oncol. 2002 Dec 15;20(24):4684-91.
9. National Institute for Health and Clinical Excellence. Guidance on the use of temozolomide for the treatment of recurrent malignant glioma (brain cancer) [internet]. London; 2001. Disponible en: http://publications.nice.org.uk/guidance-on-the-use-of-temozolomidefor-the-treatment-of-recurrent-malignant-glioma-brain-cancer-ta23.
10. Hart MG, Grant R, Garside R y cols. Temozolomide for high grade glioma (review). s. l.: The Cochrane Collaboration; 2010.
11. Wagner S, Warmuth-Metz M, Emser. A treatment options in childhood pontine gliomas. J Neurooncol. 2006 Sep;79(3):281-7.
12. Perilongo G. Considerations on the role of chemotherapy and modern radiotherapy in the treatment of childhood. J Neurooncol. 2005 Dic;75(3):301-7.
13. Massimino M, Spreafico F, Riva D et al. A lower-dose, lower-toxicity cisplatin-etoposide regimen for childhood progressive low-grade glioma. J. Neurooncol. 2010 Oct;100(1):65-71
14. Akyüz C, Demir HA, Varan A et al. Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center. Childs Nerv Syst. 2011;28(1):111-5.
2. Saran F. Recent advances in paediatric neuro-oncology. Curr Opin Neurol. 2002 Dic;15(6):671-7.
3. Hargrave D. Paediatric high and low grade glioma: the impact of tumour biology on current and future therapy. Br J Neurosurg. 2009 Ago;23(4):351-63.
4. Qaddoumi I, Sultan I, Broniscer A. Pediatric low-grade gliomas and the need for new options for therapy: Why and how? Cancer Biol Ther. 2009 Ene;8(1):4-10.
5. Massimino M, Spreafico F, Cefalo G et al. High response rate to cisplatin/etoposide regimen in childhood low-grade glioma. J Clin Oncol. 2002 Oct 15;20(20):4209-16.
6. Kuo DJ, Weiner HL, Wisoff J, Miller DC et al. Temozolomide is active in childhood, progressive, unresectable, lowgrade gliomas. J Pediatr Hematol Oncol. 2003 May;25(5):372-8.
7. Rutka JT, Kuo JS. Pediatric surgical neuro-oncology: current best care practices and strategies. J Neurooncol. 2004 Ago-Sep;69(1-3):139-50.
8. Lashford LS, Thiesse P, Jouvet A et al. A United Kingdom Children‘s Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. Temozolomide in malignant gliomas of childhood: a United Kingdom Children‘s Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. J Clin Oncol. 2002 Dec 15;20(24):4684-91.
9. National Institute for Health and Clinical Excellence. Guidance on the use of temozolomide for the treatment of recurrent malignant glioma (brain cancer) [internet]. London; 2001. Disponible en: http://publications.nice.org.uk/guidance-on-the-use-of-temozolomidefor-the-treatment-of-recurrent-malignant-glioma-brain-cancer-ta23.
10. Hart MG, Grant R, Garside R y cols. Temozolomide for high grade glioma (review). s. l.: The Cochrane Collaboration; 2010.
11. Wagner S, Warmuth-Metz M, Emser. A treatment options in childhood pontine gliomas. J Neurooncol. 2006 Sep;79(3):281-7.
12. Perilongo G. Considerations on the role of chemotherapy and modern radiotherapy in the treatment of childhood. J Neurooncol. 2005 Dic;75(3):301-7.
13. Massimino M, Spreafico F, Riva D et al. A lower-dose, lower-toxicity cisplatin-etoposide regimen for childhood progressive low-grade glioma. J. Neurooncol. 2010 Oct;100(1):65-71
14. Akyüz C, Demir HA, Varan A et al. Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center. Childs Nerv Syst. 2011;28(1):111-5.
How to Cite
Castaño González, A., Angarita Ribero, C. T., & Guzmán Cruz, P. C. (2012). Metastatic Brainstem Glioma in Children: A Case Report and Review. Universitas Medica, 54(2), 261–267. https://doi.org/10.11144/Javeriana.umed54-2.gtcm
Issue
Section
Case Reports